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OCR: ist be used Isotonic or hypertonic saline infusion n mia and with extreme caution to treat hyponatra ons such asshould be reserved for emergency situat on. Great associated fits, stupor, or marked confus ction of care should be taken to avoid rapid corr er of hyponatraemia, irrespective of the man is (osmotic treatment, or central pontine myelinoly he rate of demyelination syndrome) may ensue. T cceed increase in plasma sodium should not e 0.5mmol/l/h (12mmol/1/24h)